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The question of long-term use To make the matter more complex, initial studies seem to suggest people who lose weight with GLP-1s will need to continue taking the drugs in order to keep the weight off
Later doses may seem weaker, throwing off your weight-loss or blood-sugar goals
How Rapid Weight Loss Increases Gallstone Risk When the body loses weight quickly, the liver releases more cholesterol into bile, and the gallbladder contracts less frequently
