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95% CI 0.83 to 0.99), although to a lesser degree than SGLT-2 inhibitors

Note that a GLP-1-FGF21 fusion protein exhibits enhanced glycemic and body weight control superior to combination therapy using separate analogs of GLP-1 and FGF21 (Boettcher, B.R

That study will provide insights into the potential of GLP-1 RAs to modify the disease course in HFpEF patients

Although preclinical data generally suggest a positive impact of adiponectin on bone homeostasis through the reduction in osteoclast activity and the increase in osteoblastic differentiation, clinical studies present conflicting results

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AOM semaglutide also showed its largest quarter-over-quarter percentage point increase since the start of the study period, a trend likely driven by approval of the oral formulation of Wegovy in late 2025