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Improved glucose clearance reduces blood sugar spikes, easing the demand on insulin and supporting healthier post-meal GLP-1 signaling

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In these patients, especially those with heart or kidney disease, the drugs improved blood sugar control, reduced the risk of heart and kidney complications, supported weight loss, and lowered the risk of early death

34,39,177 The rise in cAMP activates protein kinase A (PKA), which then promotes the synthesis and secretion of insulin and inhibits the release of glucagon

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[PubMed] [Google Scholar] 368.Goke R., Conlon J.M