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Additionally, significant changes were noted in the composition of the bone matrix of these animals, with decreased enzymatic cross-linking of the collagenous matrix, which clearly worsened the compromised biomechanical strength and contributed to the observed bone fragility [44]

[118] [119] Biocon plans to offer generic semaglutide in Mexico and Saudi Arabia

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For tirzepatide specifically, common side effects include constipation , diarrhea , headaches , and body aches

Vomiting and diarrhea were also relatively common

Alcohol can suppress glucose production in the liver