glp-1 side effects long term Long-term Success of GLP-1s Hinges on More Than Just a Prescription Ozempic & GLP-1 Drugs :

By reducing autophagy via the GLP-1R-ERK1/2-histone deacetylase 6 (HDAC6) signaling pathway, GLP-1 treatment enhances diabetic retinopathy (DR)

Symptoms of MVA were measured by five dimensionsonly the physical limitation score improved after 12 weeks of liraglutide treatment when compared to the control period

Although GLP-1RAs are generally well tolerated, they are associated with gastrointestinal symptoms, pancreatic complications, and occasionally retinopathy, renal events, or injection-site reactions (Table 1)

Birth defects occur in 3-4% of pregnancies among women with these conditions versus 2-3% in the general population

Chang YF, Zhang D, Hu WM, Liu DX, Li L

These side effects overlap with common complaints about many GLP-1 related digestive issues , though the mechanisms are entirely different