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In clinical application, sirolimus, an outstanding representative of mTOR inhibitors, is widely used to prevent rejection after solid organ transplantation and protect the safety of transplanted organs through its powerful immunosuppressive effect

Nat Commun 9(1):5008 Viader A, Wright-Jin EC, Vohra BPS, Heuckeroth RO, Milbrandt J (2011) Differential regional and subtype-specific vulnerability of enteric neurons to mitochondrial dysfunction

Additionally, these genetically tailored microbes can be finely controlled in a laboratory setting using modern techniques like near-infrared (NIR) light and ultrasound, allowing for precise adjustments to their activity and behavior

Involvement of increased expression of transient receptor potential melastatin 8 in oxaliplatin-induced cold allodynia in mice