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Improved range of motion and functional improvement usually show up around weeks 1-2

This is likely due to an increase in miniature synaptic activity brought about by increasing dendritic spine densities and altering the morphological phenotype of postsynaptic spines

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In addition, acetyl-L-Carnitine administration affects protein synthesis, increasing the intracellular amino acid pool useful in speeding up the energy metabolism of Sertoli cells
