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8 Navigating the course of neuroinflammation and microglial activation: insights into multiple sclerosis, Alzheimers disease, and Parkinsons disease Microglia, crucial cells within the CNS, have their origins in the yolk sac and undergo a differentiation process regulated by interferon regulatory factor 8 (IRF8) and the transcription factor PU.1 (233)

Available online: 231.Chen Z., Shi T., Zhang L., Zhu P., Deng M., Huang C., Hu T., Jiang L., Li J

While the uptake of oral liposomes with negative zeta potential by mononuclear phagocytic system cells increases, formulations with positive zeta potential may interact with proteins and cause undesirable effects [58,59]

In damaged AMD cells, excessive production of ROS induces mitophagy through a process involving the p62/Nrf2 signaling pathway with this having a central role in AMD pathogenesis (93)

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The role of ABC transporters in drug resistance, metabolism and toxicity
