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Activation of caspases and proapoptotic factors contributes to inflammation and initiates cellular apoptosis [288]

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On the other hand, the stimulation of NF-B and AP-1 enhances the amount of matrix metalloproteinases (MMPs) in dermal fibroblasts, leading to the degradation of the extracellular matrix (ECM) and a delay in the healing process of wounds

A cross-sectional study analyzed the data from data from the National Health and Nutrition Examination Survey for 3,675 participants (aged 60 and older) to investigate relationships between dietary flavonoids and stroke risk, the results suggesting that flavonoid-rich dietary patterns are protective against stroke in older adults (56)