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10.1515/chem-2022-0204 Open Chem

doi:10.3390/ijms18010208

These receptors represent the natural targets for endogenous GHRH and serve as the principal regulatory mechanism for growth hormone synthesis and secretion

Thyroid axis changes Rapid weight loss consistently affects the hypothalamic-pituitary-thyroid axis

Despite the success in preclinical studies, translation of nose-to-brain efficacy to the clinics remains challenging