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Topical antihistamine creams are not recommended for this purpose, as they carry a risk of contact sensitisation and are not supported by UK clinical guidance (BNF

When to Contact a Healthcare Professional Travellers should seek medical advice if they experience: severe nausea or vomiting persistent dehydration missed doses with uncertainty about timing damaged medication pens Healthcare professionals can provide guidance specific to the medication being used

Braak H, Ghebremedhin E, Rb U, Bratzke H, Del Tredici K

Retatrutide adds a third arm glucagon receptor agonism which preclinical and Phase 2 data suggest contributes additional hepatic lipid mobilization and energy expenditure effects not observed with mono- or dual-agonist compounds

While helpful for some, results vary widely, and long-term success depends on adherence and individual factors

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