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They do not contain live bacteria, they do not colonize the gut, and they do not produce postbiotic metabolites like P9 or butyrate

376378 In a dexamethasone-induced muscle atrophy model, Ex-4 ameliorated muscle atrophy by inhibiting muscle atrophy factor and enhancing myogenic factors (MyoG and MyoD), thereby increasing muscle mass and function

Treatment of Apoe / Irs +/ mice (a mouse model of insulin resistance, metabolic syndrome, and atherosclerosis) with either lixisenatide or liraglutide decreased atherosclerotic lesion size, generated more stable plaques with fewer lesional leukocytes, and resulted in reduced necrotic cores and thicker fibrous caps (4)

The Philadelphia Inquirer

A 2022 study involving people with Irritable Bowel Syndrome (IBS) found that ROSE 010, a GLP-1 receptor agonist, reduced IBS pain during flare-ups, primarily in female participants