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The salutary effects of GLP-1RA on endothelial function could also be exploited for ED amelioration 96 , as the GLP-1 receptor was detected in endothelial cells and GLP-1RA were found to affect endothelial function by stimulating nitric oxide production 99

Clinically, this can present as an initial strong response followed by diminishing returns despite adherence and dose optimization

Patients should consider temporarily reducing intake of high-sulfur foods, including: Red meat, poultry, and eggs Dairy products (milk, cheese, yogurt) Cruciferous vegetables (broccoli, cauliflower, Brussels sprouts, cabbage) Allium vegetables (garlic, onions, leeks) Legumes and certain nuts Protein supplements, particularly whey-based products Rather than eliminating these nutritious foods entirely, patients can moderate portions and observe which specific items trigger symptoms

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