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In theory, the transfer to human milk of GLP-1 agonists may be low, as they are large peptide molecules ( Supplement 3 )

Furthermore, in signaling studies that used cell lines with recombinantly expressed human GIPR or GLP-1R, tirzepatide stimulated cyclic adenosine monophosphate (cAMP) accumulation by either receptor with potency similar to that of native GIP and approximately 13-fold weaker than that of native GLP-1 [1]

Or these GLP-1 agonist drugs may have a direct anti-cancer effect by impacting the immune microenvironment, the microbiome, and may be anti-inflammatory

[DOI] [PubMed] [Google Scholar] 163.Romariz L., Arajo B., Barbosa L.M., Jain R., Porto Silva Janovsky C.C

To maintain weight loss after stopping GLP-1, focus on a diet rich in protein and fiber to help you feel full and manage your appetite naturally