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& Berthoud, H
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When Key Decisions Occur in Willows Intake-Led Program 4
when cardiac cytoplasmic Na + and Ca 2+ concentrations and mitochondrial Ca 2+ were measured fluorometrically in isolated ventricular myocytes from rabbits and rats, the results evidenced that empagliflozin directly inhibited NHE flux, caused by a reduction in cytoplasmic Na+ and Ca 2+ concentrations and an increase in mitochondrial Ca 2 [118]
[DOI] [PubMed] [Google Scholar] 18.Nersessian RS, da Silva LM, Carvalho MA, Silveira SQ, Abib AC, Bellicieri FN, et al
Further large-scale, randomised controlled trials with longer follow-up are needed before these medications can be considered an evidence-based treatment option for alcohol use disorder
