combination therapy with glp-1 receptor agonist and sglt2 inhibitor Schematic illustration of monoagonists, dual agonists triple Combining glucagon-like peptide-1 receptor agonists
Description
Baseline glycemic control : Patients with higher HbA1c levels may require more aggressive dose escalation, though this must be balanced against tolerability

The most common include nausea, vomiting, gastrointestinal discomfort, and, less frequently, headaches or fatigue

He's careful not to overclaim the mechanism
Incretin therapy is the second line of treatment for T2D, improving both blood glucose regulation and weight loss
[DOI] [PubMed] [Google Scholar] 95.Zhang Q., Wu Y., Fei X

20 TECOS (2015) did not show an increased risk of HF in patients taking sitagliptin for treatment of type 2 diabetes
