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Why this matters: This clinical breakthrough demonstrates that a diabetes treatment can do more than manage blood sugarit can protect vital organs, reduce complications, and extend life expectancy

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Spironolactone is a potassium-sparing diuretic used for hypertension and fluid retention, while semaglutide is a GLP-1 receptor agonist for weight loss and diabetes management

Exercise and diet help slow regain by 3040%, but they do not prevent the underlying hormonal reset

Spencer Nadolsky about his involvement with Sequence, which eventually became WeightWatchers Clinic: I was the medical director for Sequence (now WeightWatchers Clinic) at the beginning

The researchers recruited 72 patients with type 1 diabetes and obesity, based on their BMIs