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The researchers behind a systematic review of existing clinical trials concluded that the use of drugs in the GLP-1 RA class, like Ozempic, was associated with an increased risk of gallbladder diseases, according to a 2022 article published in the journal JAMA Internal Medicine

The FDA's preliminary evaluation found no evidence that GLP-1 medications cause suicidal ideation, though monitoring continues

The authors of the January study stressed that it was observational, so its impossible to tell from the data if any of the effects are a direct result of taking a GLP-1RA

Sermorelin is often preferred for hormone optimization, anti-aging, and improving overall vitality

Is there a step therapy requirement, do I have to try another medication first

Limited data from small observational and retrospective studies suggest the safety and efficacy of tirzepatide in these populations, illustrating the need for dedicated clinical trials.209 Additionally, the potential neuroprotective effects of tirzepatide remain unclear