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10.2337/db17-1385 [DOI] [PMC free article] [PubMed] [Google Scholar] Alexander, S

Strong reimbursement frameworks and the early adoption of cutting-edge GLP-1 therapies helped sustain market leadership

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The "Natural GLP-1 Support" Claim: The company claims "Natural GLP-1 Support" and mentions berberine in marketing materials, with language referencing appetite management and metabolic support

Combined SGLT2i and GLP-1RA therapy resulted in a significantly lower risk of all-cause death, non-fatal myocardial infarction, and non-fatal stroke at 12 months than SGLT2i monotherapy (HR, 1.77

Without peer-reviewed human data showing pharmacokinetics and downstream effects, claims remain theoretical