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We are also finding out that the impacts of GLP-1 agonists go beyond weight loss, manifesting in sometimes surprising ways

In 2017, a post hoc pooled analysis of RCTs on liraglutide demonstrated comparably low incidences of depression and anxiety in both the liraglutide and placebo cohorts

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It is non-bloody and often occurs in the setting of poorly controlled diabetes

The result is stool that becomes progressively drier and harder, making it more difficult to pass

BMJ Medicine
