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Asbaghi O, Ghanbari N, Shekari M, et al

Adherence to and persistence with antidiabetic medications and associations with clinical and economic outcomes in people with type 2 diabetes mellitus: a systematic literature review

doi: 10.2337/db13-0140 21 MeierJJ
Weight reduction (denoted henceforth with the minus [-] sign) ranges from 2.8 to 4.8% total body weight loss (TBWL).55,56,70,87 Additional benefits of orlistat include reduced total cholesterol, LDL, fasting glucose, and systolic and diastolic blood pressure (Table 5).8890 Side effects arise from the reduced fat absorption, including flatulence, fecal urgency, fecal incontinence, and fat-soluble vitamin deficiencies, which result in high rates of treatment discontinuation, and low clinical use.87,91 Table 5

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