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Regulation and Physiology of the Ghrelin-LEAP2 System Biosynthesis and Post-Translational Processing of Ghrelin and LEAP2 The human ghrelin gene ( GHRL ), located at chromosome 3p26-p25, encodes a 117-amino-acid polypeptide known as preproghrelin, comprising a 23amino-acid signal peptide and a 94amino-acid proghrelin segment (Fig

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Table 9 provides the efficacy results for Studies 5 and 6

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