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In this randomized, double-blind, and placebo-controlled trial, the peptide demonstrated unprecedented results over a 48-week period: Significant Weight Reduction: In the highest dosage group evaluated, a dose-dependent reduction in body weight of up to 24.2% was achieveda figure that significantly surpasses previously published results for comparable substances in obesity and metabolic research

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1 Other benefits and cardiovascular safety The PROactive trial showed that pioglitazone reduced the risk of ischaemic events, including non-fatal myocardial infarction and stroke, in people with pre-existing cardiovascular disease