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The Gila monster (Heloderma suspectum), a unique lizard known for its binge-eating behavior, produces the hormone exenatide, the basis for diabetes medications such as Ozempic and Mounjaro

A Nature study of 27,885 people identified gene variants that predict GLP-1 weight loss and nausea risk, including one specific to Mounjaro users.

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It has a long history of use in traditional Chinese medicine
