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Pharmacological inhibition of mTORC1 with agents such as rapamycin suppresses p-S6 levels and has been shown to promote the expansion and stability of functional Tregs, underscoring the therapeutic relevance of p-S6 as both a biomarker and a pharmacodynamic readout in immunomodulatory interventions

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The medical community regards substance addiction as a chronic condition: While it can be effectively managed (with abstinence), it is likely to progress in severity without treatment