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32,33 Nevertheless, its duration of action is rather ephemeral, lasting a mere 12 min within the circulatory system under typical physiological conditions

d PIONEER, 6 was designed to document cardiovascular safety only

Pharmacol Res

Further, the recent announcements will not impact costs for Medicaid enrollees as they already pay little or no copays for prescription drugs, and the costs of purchasing drugs directly from manufacturers through TrumpRx will likely still be prohibitive for people on Medicaid who must have a low income to qualify for the program

Wider reach

Secondly and thirdly, we did two analyses to assess the potential effect of informative censoringone analysis using time varying inverse probability of censoring weighting to account for censoring due to drug switching or discontinuation between the two exposure groups, mortality, and administrative censoring during the follow-up and one analysis using an intention-to-treat exposure definition (that is, patients were followed regardless of treatment discontinuation or switching) with up to one year of follow-up (which was implemented to minimise the effect of exposure misclassification in this analysis)