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4 One such instance for which states have this flexibility is for agents when used for anorexia, weight loss, or weight gain. Hence, states that participate in MDRP are not required to cover agents for weight loss and may elect not to cover anti-obesity medications (AOMs) such as Saxenda, Wegovy, and Zepbound for their weight loss indications

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But preclinical studies have found these drugs may also have an effect on the brain

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They work by mimicking the behavior of Glucagon-Like Peptide 1, a naturally occurring hormone that triggers the pancreas to release insulin, slow digestion and reduce appetite and hunger