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Phentermine - Clinical Pharmacology 12.1 Phentermine Mechanism of Action Phentermine is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, amphetamine (d- and d/l-amphetamine)
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In the STEP 1 trial, participants lost an average of 14.9% of body weight over 68 weeks

J Physiol 28, 325353 (1902)

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