glp-1 receptor agonists brand names are commonly used medications to treat Type 2 Diabetes. They are subcutaneous injections, so many patients mistaken these medications for insulin. However, GLP-1's are very different. They work primarily on ANSE1024_0051_table_a.jpg

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A meta-analysis of seven SURPASS clinical trials in participants with T2DM showed the hazard ratios comparing tirzepatide versus controls of 0.80 (95% CI, 0.57 1.11) for 4-MACE, 0.90 (95% CI, 0.50 1.61) for cardiovascular death, and 0.80 (95% CI, 0.51 1.25) for all-cause mortality (264)

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A clinical trial in 2015 linked an undisclosed GLP-1 to significant improvements in OSA severity, while a 2016 clinical trial found that weight loss resulting from liraglutide was significantly associated with a reduction in the apnea-hypopnea index (AHI)

102 , 103 Daily dosing and pill burden may also pose practical challenges in long-term use, highlighting the need to tailor treatment choices to individual patient needs and preferences

On the flip side, the drugs can cause gastrointestinal problems including diarrhea, constipation, nausea and vomiting