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GLP-1GIPlanifibranor, a single-molecule agonist of GLP-1R, GIPR, PPAR, PPAR and PPAR, shows promising therapeutic efficacy against obesity-linked metabolic dysfunction in vitro and in mouse models via synergistic incretin and PPAR activity.

Hjbjerg Lassen, MD, MSc, PhD and colleagues from CTCPR - Center for Translational Cardiology and Pragmatic Randomized Trials, published in the European Journal of Preventive Cardiology, explored the potential population-level cardiovascular impact of implementing semaglutide (2.4 mg) in Denmark based on the eligibility criteria from the landmark SELECT trial

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