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4.2 Heart failure drugs According to the current guidelines of ECS ( The standard 1st line therapy for HF includes quadruple combination of SGLT2 inhibitor, ACEi (angiotensin converting enzyme inhibitor)/ARNI (angiotensin receptorneprilysin inhibitor), betablocker and MRA (mineralocorticoid receptor antagonist)

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It preserves some underlying structures like nerves and blood vessels and takes tension off the closure

[DOI] [PubMed] [Google Scholar] 52.Kanoski SE, Rupprecht LE, Fortin SM, De Jonghe BC, Hayes MR

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