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Despite inherent limitations of observational data and potential for residual confounding, the results from these observational analyses support, in line with RCT findings, combining SGLT2is and GLP-1RAs to reduce cardiovascular events in patients with diabetes in routine clinical care [12, 23, 43, 63]

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Who Is Most at Risk: Clinical and Genetic Considerations Patients experiencing significant nausea or vomiting early in treatment show higher rates of temperature dysregulation

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Available under brand names like Ozempic, Wegovy, and Rybelsus, this medication works by mimicking a natural hormone in your body called glucagon-like peptide 1 (GLP-1), which helps regulate hunger and blood sugar levels