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If retatrutide receives marketing authorisation in the future, it would likely be subject to additional monitoring indicated by a black triangle () symbol which encourages enhanced Yellow Card reporting for new medicines to help identify any rare or delayed effects not captured in pre-approval trials

Research backs up the finding

M., Obesity and Adverse Breast Cancer Risk and Outcome: Mechanistic Insights and Strategies for Intervention, CA: A Cancer Journal for Clinicians 67 (2017): 378397

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[DOI] [PubMed] [Google Scholar] 220

Preclinical work demonstrates incretin receptor gene and protein expression in female reproductive tissues such as ovary and uterine structures in animal models, supporting the concept that incretin signalling can interact with reproductive physiologyagain, not equivalent to a clinically meaningful direct vaginal mucosal effect in humans