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In addition to the common triggers mentioned, heart palpitations can also be influenced by hormonal changes, such as those experienced during pregnancy or menopause

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A further possibility is that the positive chronotropic effect could be, at least partially, mediated by sympathetic nervous system enhancement, related to the inhibition of the autonomic nervous system [18, 36, 37]

Patients with gastrointestinal conditions Pre-existing conditions like gastroparesis, inflammatory bowel disease, or severe GERD may intensify semaglutide gastrointestinal side effects