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S Korea 7.4.2.1

Because each sequence in the initial alignment has a length of 30 amino acids and each position can be mutated to one of 19 amino acids (20 if the position is gapped), this gives 570 single-step mutants in the first generation for each sequence in the training set, that is, 71,304 sequences, reducing to 69,639 sequences after removing duplicates

Green indicates concordant results, while red indicates contrasting results

Liraglutide is also marketed as a diabetes drug under the name Victoza

As GLP-1 receptor agonists continue to revolutionize diabetes and weight management, understanding their full range of effectsincluding potential risks to visionwill be crucial in ensuring their safe use

doi: 10.1016/0306-4522(83)90152-5