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[Literature Review] AI-Driven Efficient De Novo design of GLP-1RAs with Extended Half-Life and Enhanced Efficacy This paper introduces an AI-driven pipeline for efficient de novo design of peptide drugs, focusing on GLP-1 receptor agonists (GLP-1RAs) with extended half-life and enhanced efficacy

doi: 10.1038/s41598-021-00654-3

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Through mimicking the GLP-1 hormone in charge of triggering insulin, slowing digestion and appetite, these medications extend the hormones effects to induce notable fullness long after eating