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Nonetheless, their favorable safety profile in CKD (no dose adjustment required for most agents) and the absence of increased hypoglycemia risk support their use in appropriate patients [115,145]

They should not open sealed medication containers
If mornings are problematic, an early injection provides maximal effect when you need it

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Researchers who jump to high doses quickly experience more pronounced cardiovascular effects because the glucagon receptor gets activated intensely before the body can adapt

2016 May 27;118(11):17031705
