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Supplement timing The supplements commonly taken alongside tirzepatide , including B12, electrolytes, and digestive enzymes, are generally unaffected by injection day selection

Risk mitigation strategies include a 24-hour clear liquid diet before surgery and enhanced airway protection measures

Mounjaro is a highly effective, US-licensed weight loss treatment that has shown in clinical trials to help patients achieve up to 20% body weight loss

UK guidance favours individualised risk assessment rather than universal cessation for all patients

The SURPASS program tested tirzepatide in type 2 diabetes across SURPASS-1 through SURPASS-5

The FORTRESS study found an excess risk of 1.5 (95% CI = -1.1 to 4.1) oral cleft cases per 1,000 infants exposed to topiramate during the first trimester
