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[220] The decision regarding frequency of use should also consider other sleep hygiene measures and non-pharmacological interventions that may reduce the need for medication

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Other research also links the drug to blood clots in the legs, including DVT and other thromboembolic events

Semaglutide therapy also does not alter resting metabolic rate, therefore justifying subsequent therapy to adjust energy intake during metabolic rate adjustments to support long-term weight loss [23, 24]
