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This suppression was observed consistently across variable and fixed dosing paradigms

In obesity management, liraglutide, semaglutide, and tirzepatide significantly reduce body mass and ameliorate cardiovascular and metabolic risk factors

Endocrinology 137 , 36743680 (1996)

They may pause therapy to reduce aspiration risk during anesthesia

In several RCTs, GLP-1RAs, when used alone or in combination with other hypoglycemic agents including metformin, sulfonylurea, DPP-4 inhibitor, thiazolidinedione, and sodium-glucose cotransporter 2 inhibitor, showed superior or non-inferior blood glucose lowering ability compared to insulin treatment [64,65]

Efficacy and safety comparison between liraglutide as add-on therapy to insulin and insulin dose-increase in Chinese subjects with poorly controlled type 2 diabetes and abdominal obesity