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GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) are the primary members (57)

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Both in vitro and in vivo studies have provided evidence that Ex-4 can significantly inhibit breast cancer cell proliferation by suppressing NF-B signaling activation and the expression of its downstream target genes, vascular endothelial growth factor (VEGF) and interleukin-8(IL-8) [55]

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What this trial could tell us If results are positive, we would expect to see statistically significant differences between the resM group and placebo group in body weight, BMI, and relevant biomarkers like fasting glucose, insulin, and possibly GLP-1 levels