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Description
Exenatide and lixisenatide are based on the peptide exendin-4, while the rest are GLP-1-based agents
95% CI, 0.511.08)
In all in vitro and in vivo models used, tirzepatide was able to stimulate glucose-dependent insulin secretion via GIP and/or GLP-1 receptor activation
However, this mechanism remains hypothetical and requires further clinical validation
Preventive effects of exenatide on endothelial dysfunction induced by ischemia-reperfusion injury via KATP channels
The sample sizes for both in vitro transfection studies (Hepa1-6 and HepG2 cells) and in vivo studies (Balb/c and DIO mice) were predetermined
