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But as of today, Glucagon-Like peptide 1 receptor agonists (GLP1-RAs), sodium-glucose cotransporter 2 inhibitors (SGLT2is), dipeptidyl peptidase 4 inhibitors (DPP4is) and mineralocorticoid receptor antagonists, are quickly becoming part of, if not the drugs of choice for diabetes, especially in cases with heart, kidney or liver comorbidities [9,10,11,12]

doi: 10.1152/ajpendo.1985.248.5.E507

Recently, the compounding of weight-loss drugs has surged as Lilly and Novo have struggled to meet the high demand for their new medications

FPG levels decreased in both the sitagliptin and saxagliptin arms (by 16.2 mg/dL and 10.8 mg/dL, respectively)
Coexpression of glucagon-like peptide-1 (GLP-1) receptor, vasopressin, and oxytocin mRNAs in neurons of the rat hypothalamic supraoptic and paraventricular nuclei: Effect of GLP-1(7-36)amide on vasopressin and oxytocin release

FACT: No matter how hard someone tries or how many lifestyle changes they make, there are factors like genetics or medical conditions that can make losing weight very difficult
