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These systemic metabolic changes are likely to contribute to dysregulation of cerebrospinal fluid dynamics, primarily hypersecretion but with a possible additional effect of reduced clearance resulting in the core feature of raised intracranial pressure.

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Each red bar quantifies the GLP-1 utilization per 1,000 Members of the plan, from a low of 1.6 in 2021 to 7.3 in 2023H1

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