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4b) with similar potency but lower efficacy (~10%) than glucagon (ESM Table 4)

When starting GLP-1 medications, doctors usually begin with a low dose and increase it slowly over several weeks or months to reduce side effects, especially nausea and stomach upset

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However, no large-scale clinical studies have measured semaglutide levels in breast milk, so absolute data is unavailable

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Other options are in development as well, but more study is needed before they are approved for chronic weight-management treatment
