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Description
Other residues, although accessible, were either clustered near symmetry axes ( e.g ., D12, F96, K142), exhibited lower surface exposure ( e.g ., D12, E88), or were located in more flexible sections ( e.g ., E81 in the long loop), making them less suitable for conjugation
GLP-1 signals to the brain that the stomach is full, stimulates the pancreas to produce insulin in response to meals, and slows gastric emptying (food leaves the stomach more slowly, extending the feeling of fullness)
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10.1186/s10194-023-01631-z
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