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Abdominal obesity, in addition to high blood sugars, high cholesterol, and high blood pressure, is a key component of metabolic syndrome, said Prasad

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[36] reported that exendin-4 treatment decreases hepatic glucose output at hyperinsulinemic states and promotes hepatic insulin signaling by potentiating tyrosine phosphorylation of the insulin receptor substrate-2 in 90% pancreatectomized diabetic rats fed high fat (40% energy from fat) diets

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Regulation of the hypothalamic-pituitary-adrenocortical stress response