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40% were assigned female at birth and the population had mean HbA 1c of 8.1%, BMI of 35.3 kg/m 2 , (Table 1)

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It's an adaptive metabolic response to caloric restriction
Many people begin noticing appetite changes within the first few weeks, though individual results vary

Tirzepatide, a dual GIP and GLP-1 receptor agonist approved by the FDA for type 2 diabetes (Mounjaro) and chronic weight management (Zepbound), may indirectly affect menstrual cycles in some women

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