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Su et al., 2015) have shown that GLP-1RA treatment has a fracture risk reduction effect in patients with T2DM
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[DOI] [PMC free article] [PubMed] [Google Scholar] 113.Mullins R.J., Mustapic M., Chia C.W., Carlson O., Gulyani S., Tran J., Li Y., Mattson M.P., Resnick S., Egan J.M., et al

Three-quarters of the trials participants taking the highest dosage of orforglipron no longer met the criteria for type 2 diabetes defined by the American Diabetes Association
Recent research has revealed that under specific circumstances, lactic acid can even become the dominant supplier of pyruvate for the heart, highlighting its importance (44)
Source: GLP-1.Reviews editorial walkthrough on April 29, 2026
