oral glp-1 agonists Are Serious Anesthesia Risks of Semaglutide and Other Under-Recognized? Case Reports of Retained Solid Gastric Contents in Patients Undergoing Anesthesia The Impact of GLP-1 Receptor

Initially developed for glycemic control in diabetic patients, recent clinical findings have revealed their profound effects on weight loss, cardiovascular health, and metabolic regulation

So lets talk about GLP-1

While the effects of the dual incretin receptor agonist were promising, the changes in glycemic control and body weight were not statistically different from liraglutide at the single dose tested

doi: 10.3390/ijms22073330 [DOI] [PMC free article] [PubMed] [Google Scholar] 77

In these studies, 80% of people with POMC or PCSK1 deficiencies achieved at least 10% weight loss after one year

Moreover, chronic treatment with liraglutide showed an increase in stem cell proliferation and differentiation into mature neurons in APP/PS1 mice and controls at all ages, which may have beneficial effects in neurodegenerative disorders like AD (168)